Module 4 Part 1: Psychological Disorders

A psychological disorder, also known as a mental disorder or psychiatric disorder, is a condition characterized by abnormal thoughts, feelings, behaviors, or a combination of these that cause significant distress or impairment in an individual's daily life.

These disorders can affect a person's ability to function in various aspects, including personal relationships, work, and social activities.

Key Features of Psychological Disorders

Abnormality: The thoughts, feelings, or behaviors are significantly different from what is considered typical or normal in a given culture.

Distress: The condition causes substantial emotional or psychological distress to the individual.

Impairment: The disorder leads to significant impairment in important areas of functioning, such as work, school, or social relationships.

Duration: The symptoms persist over a period of time, rather than being a temporary reaction to a stressful event.

Deviation from Developmental Norms: The behavior is not appropriate for the individual's developmental stage. 

The medical model is a framework for understanding psychological disorders as medical diseases with biological origins. This model views mental health issues similarly to physical health problems, focusing on their biological basis and often emphasizing diagnosis and treatment through medical interventions.

Biological Basis: The medical model posits that psychological disorders have physiological causes, such as genetic predispositions, neurochemical imbalances, brain abnormalities, or infections. Research in this model often focuses on understanding these biological underpinnings.

Diagnosis: Disorders are diagnosed based on specific criteria, usually outlined in diagnostic manuals such as the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) or the International Classification of Diseases (ICD). Diagnosis involves identifying symptoms and matching them to established categories of mental illnesses.

Treatment. Treatment typically involves medical interventions, such as medications (e.g., antidepressants, antipsychotics, or mood stabilizers) that target biological causes. Other treatments can include medical procedures like electroconvulsive therapy (ECT) or newer technologies such as transcranial magnetic stimulation (TMS).

The medical model emphasizes objective measurements and assessments, such as brain scans, blood tests, or other laboratory tests to identify biological markers of disorders.

Strengths of the Medical Model

Provides a structured and systematic approach to diagnosing and treating mental health issues.

Medical treatments can be highly effective for certain disorders, especially those with clear biological components.

Promotes research into the biological causes of mental disorders, leading to the development of new treatments.

Limitations of the Medical Model

May neglect psychological, social, and environmental influences on mental health.

Viewing mental health issues purely as diseases can contribute to stigma and a sense of helplessness in individuals.

Simplifies complex human experiences to mere biological factors, potentially missing the holistic view of mental health.

Example: A patient diagnosed with major depressive disorder (MDD) under the medical model might receive an evaluation to identify neurochemical imbalances. Treatment could involve prescribing antidepressants to adjust serotonin levels in the brain, combined with follow-up assessments to monitor biological responses to the medication.

In summary, the medical model views psychological disorders as biologically-based diseases, emphasizing diagnosis and treatment through medical interventions. While it offers a scientific and effective approach for certain conditions, it also faces criticism for its potential to overlook the broader context of mental health issues.

Epigenetics is the study of heritable changes in gene expression that do not involve changes to the underlying DNA sequence. These changes can affect how genes are turned on or off and can be influenced by various environmental factors.

Epigenetics provides a mechanism for how environmental factors can influence gene expression, thereby affecting psychological traits and behaviors. This interaction helps explain why identical twins with the same genetic makeup can exhibit different behaviors and psychological conditions when exposed to different environments.

Chronic stress can lead to epigenetic changes that affect the regulation of stress-response genes. These changes can contribute to the development of mental health disorders such as depression, anxiety, and PTSD. For example, alterations in DNA methylation patterns of genes involved in the hypothalamic-pituitary-adrenal (HPA) axis can affect stress resilience and vulnerability.

Early life experiences, including parental care, trauma, and social environment, can result in lasting epigenetic modifications. These changes can influence cognitive development, emotional regulation, and susceptibility to mental health disorders later in life. For instance, children who experience neglect or abuse may have epigenetic changes that affect their stress-response systems and increase the risk of developing psychological disorders.

Epigenetic mechanisms play a role in the development of addiction. Exposure to addictive substances can cause epigenetic modifications in genes associated with reward and addiction pathways in the brain. These changes can alter an individual's susceptibility to addiction and affect the course of the disorder.

Epigenetic changes can impact cognitive function and the aging process. Environmental factors, such as diet and physical activity, can influence epigenetic marks that regulate genes involved in cognitive processes and neuroplasticity. Understanding these mechanisms can provide insights into age-related cognitive decline and neurodegenerative diseases.

Understanding the influence of epigenetics on psychology offers several benefits:

Insights into epigenetic mechanisms can lead to personalized therapeutic interventions that target specific epigenetic modifications.

Identifying epigenetic markers associated with psychological disorders can facilitate early detection and preventive strategies.

Recognizing the role of both genetic and environmental factors provides a more comprehensive understanding of psychological disorders and human behavior.

Epigenetics bridges the gap between genetics and environment, showing how external factors can influence gene expression and, consequently, psychological traits and behaviors. By understanding these mechanisms, researchers can develop better interventions and prevention strategies for mental health disorders, ultimately improving psychological well-being.

The DSM-5-TR is an updated version of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). It is a comprehensive classification system used by clinicians and researchers to diagnose and classify mental disorders. The "Text Revision" (TR) indicates that this edition includes updates and clarifications based on new research and clinical experience since the publication of the DSM-5.

Key Features of DSM-5-TR

The DSM-5-TR provides standardized criteria for diagnosing mental disorders. It categorizes mental health conditions based on symptomatology and clinical presentation.

The text revision includes updates to diagnostic criteria, descriptions, and terminology based on the latest scientific evidence and clinical practice. These revisions may include changes in diagnostic thresholds, the addition of new disorders, and the reorganization of existing categories.

Emphasizes the importance of cultural context in diagnosing mental disorders. It includes cultural formulations and guidance on how to consider cultural factors in clinical assessment.

Incorporates dimensional measures that assess the severity of symptoms and the impact on functioning, recognizing that mental health symptoms often exist on a spectrum.

Aims to align with the International Classification of Diseases (ICD) to facilitate international use and consistency in diagnosing and coding mental health disorders.

The revisions are based on extensive research, expert consensus, and field trials to ensure that the criteria reflect current understanding and best practices in mental health care.

Example: A clinician using the DSM-5-TR to diagnose a patient with major depressive disorder (MDD) will refer to the updated criteria, which may include specific symptom thresholds and considerations for cultural context. The DSM-5-TR might also provide additional guidance on distinguishing MDD from similar disorders and using dimensional assessments to gauge the severity of the patient's symptoms.

Importance

The DSM-5-TR serves as a crucial tool for mental health professionals in diagnosing and treating patients, ensuring consistency and accuracy in clinical practice.

Researchers use the DSM-5-TR to define study populations, ensuring that research findings are applicable and comparable across different studies.

Insurance companies and policymakers use DSM-5-TR criteria to determine coverage for mental health services and to guide public health initiatives.

The DSM-5-TR (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision) organizes mental disorders into various categories to aid in diagnosis and treatment. Here are the key disorder categories included in the DSM-5-TR:

Neurodevelopmental Disorders. Examples: Autism Spectrum Disorder, Attention-Deficit/Hyperactivity Disorder (ADHD), Specific Learning Disorders.

Schizophrenia Spectrum and Other Psychotic Disorders. Examples: Schizophrenia, Schizoaffective Disorder, Delusional Disorder.

Bipolar and Related Disorders. Examples: Bipolar I Disorder, Bipolar II Disorder, Cyclothymic Disorder.

Depressive Disorders. Examples: Major Depressive Disorder, Persistent Depressive Disorder (Dysthymia), Disruptive Mood Dysregulation Disorder.

Anxiety Disorders. Examples: Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Specific Phobias.

Obsessive-Compulsive and Related Disorders. Examples: Obsessive-Compulsive Disorder (OCD), Body Dysmorphic Disorder, Hoarding Disorder.

Trauma- and Stressor-Related Disorders. Examples: Post-Traumatic Stress Disorder (PTSD), Acute Stress Disorder, Adjustment Disorders.

Dissociative Disorders. Examples: Dissociative Identity Disorder, Dissociative Amnesia, Depersonalization/Derealization Disorder.

Somatic Symptom and Related Disorders. Examples: Somatic Symptom Disorder, Illness Anxiety Disorder, Conversion Disorder.

Feeding and Eating Disorders. Examples: Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder.

Elimination Disorders. Examples: Enuresis, Encopresis.

Sleep-Wake Disorders. Examples: Insomnia Disorder, Narcolepsy, Sleep Apnea.

Sexual Dysfunctions. Examples: Erectile Disorder, Female Sexual Interest/Arousal Disorder, Premature Ejaculation.

Gender Dysphoria. Examples: Gender Dysphoria in Children, Gender Dysphoria in Adolescents and Adults.

Disruptive, Impulse-Control, and Conduct Disorders. Examples: Oppositional Defiant Disorder, Intermittent Explosive Disorder, Conduct Disorder.

Substance-Related and Addictive Disorders. Examples: Alcohol Use Disorder, Opioid Use Disorder, Gambling Disorder.

Neurocognitive Disorders. Examples: Delirium, Major and Mild Neurocognitive Disorders (e.g., due to Alzheimer's Disease, Traumatic Brain Injury).

Personality Disorders. Examples: Borderline Personality Disorder, Antisocial Personality Disorder, Narcissistic Personality Disorder.

Paraphilic Disorders. Examples: Pedophilic Disorder, Exhibitionistic Disorder, Fetishistic Disorder.

Other Mental Disorders. Examples: Other Specified Mental Disorder, Unspecified Mental Disorder. 

The prevalence of mental health disorders can vary, but some of the most commonly diagnosed mental health disorders in the United States include:

1. Anxiety disorders are among the most common mental health disorders, affecting about 18% of the adult population each year.

2. Major Depressive Disorder (MDD) affects approximately 7% of adults in the U.S. annually.
3. Bipolar disorder affects about 2.8% of U.S. adults each year.

4. Attention-Deficit/Hyperactivity Disorder (ADHD) affects approximately 8.4% of children and 2.5% of adults in the U.S.

5. Post-Traumatic Stress Disorder (PTSD) affects about 3.5% of U.S. adults annually.

6. Obsessive-Compulsive Disorder (OCD) approximately 1.2% of the U.S. population each year.

7. Schizophrenia affects about 1% of the U.S. population.

8. Approximately 7.4% of individuals aged 12 or older had a substance use disorder in the past year.

9. Eating disorders affect about 9% of the U.S. population during their lifetime.

10. Borderline Personality Disorder (BPD) affects about 1.4% of U.S. adults. 

The DSM-5-TR (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision) classifies several anxiety disorders, each characterized by excessive fear and anxiety and related behavioral disturbances. Here are the main anxiety disorders included in the DSM-5-TR:

Generalized Anxiety Disorder (GAD). Characterized by excessive anxiety and worry occurring more days than not for at least six months about various events or activities.

Symptoms

Restlessness or feeling on edge

Being easily fatigued

Difficulty concentrating

Irritability

Muscle tension

Sleep disturbances

Panic Disorder. Characterized by recurrent unexpected panic attacks, which are abrupt surges of intense fear or discomfort that peak within minutes.

Symptoms

Palpitations, pounding heart, or accelerated heart rate

Sweating

Trembling or shaking

Shortness of breath or feeling smothered

Feelings of choking

Chest pain or discomfort

Nausea or abdominal distress

Feeling dizzy, unsteady, lightheaded, or faint

Chills or heat sensations

Paresthesia (numbness or tingling sensations)

Derealization (feelings of unreality) or depersonalization (being detached from oneself)

Fear of losing control or "going crazy"

Fear of dying Specific

Phobias. Characterized by a marked fear or anxiety about a specific object or situation (e.g., flying, heights, animals, receiving an injection, seeing blood).

Symptoms

The phobic object or situation almost always provokes immediate fear or anxiety

The phobic object or situation is actively avoided or endured with intense fear or anxiety

The fear or anxiety is out of proportion to the actual danger posed by the specific object or situation

Agoraphobia. Characterized by a marked fear or anxiety about two or more of the following situations:

Using public transportation

Being in open spaces

Being in enclosed places

Standing in line or being in a crowd

Being outside of the home alone

Symptoms

Fear or avoidance of these situations because of thoughts that escape might be difficult or help might not be available in the event of developing panic-like symptoms or other incapacitating or embarrassing symptoms

Social Anxiety Disorder (Social Phobia). Characterized by a marked fear or anxiety about one or more social situations in which the individual is exposed to possible scrutiny by others.

Symptoms

Fear of acting in a way or showing anxiety symptoms that will be negatively evaluated

Social situations almost always provoke fear or anxiety

Social situations are avoided or endured with intense fear or anxiety

The fear or anxiety is out of proportion to the actual threat posed by the social situation

Separation Anxiety Disorder. Characterized by excessive fear or anxiety concerning separation from those to whom the individual is attached.

Symptoms

Recurrent excessive distress when anticipating or experiencing separation

Persistent and excessive worry about losing major attachment figures

Persistent and excessive worry about experiencing an untoward event that causes separation

Reluctance or refusal to go out, away from home, to school, to work, or elsewhere because of fear of separation

Persistent and excessive fear of or reluctance about being alone or without major attachment figures at home or in other settings

Reluctance or refusal to sleep away from home or to go to sleep without being near a major attachment figure

Repeated nightmares involving the theme of separation

Repeated complaints of physical symptoms when separation from major attachment figures occurs or is anticipated

Selective Mutism. Characterized by consistent failure to speak in specific social situations in which there is an expectation for speaking (e.g., at school) despite speaking in other situations.

Symptoms

The failure to speak is not due to a lack of knowledge or comfort with the spoken language required in the social situation

The disturbance interferes with educational or occupational achievement or with social communication 

Post-Traumatic Stress Disorder (PTSD) is a mental health condition triggered by experiencing or witnessing a traumatic event. It is characterized by persistent, distressing symptoms that affect an individual's ability to function in daily life.

Key Features and Symptoms

Exposure to Trauma

Directly experiencing a traumatic event.

Witnessing a traumatic event in person.

Learning that a traumatic event occurred to a close family member or friend.

Repeated or extreme exposure to aversive details of traumatic events (e.g., first responders).

Intrusive Symptoms

Recurrent, involuntary, and distressing memories of the traumatic event.

Recurrent distressing dreams related to the traumatic event.

Flashbacks, where the individual feels or acts as if the traumatic event is recurring.

Intense or prolonged psychological distress at exposure to cues that symbolize or resemble an aspect of the traumatic event.

Marked physiological reactions to reminders of the traumatic event.

Avoidance

Avoiding distressing memories, thoughts, or feelings about or closely associated with the traumatic event.

Avoiding external reminders (people, places, conversations, activities, objects, situations) that arouse distressing memories, thoughts, or feelings about the traumatic event.

Negative Alterations in Cognitions and Mood

Inability to remember an important aspect of the traumatic event.

Persistent and exaggerated negative beliefs or expectations about oneself, others, or the world.

Persistent, distorted cognitions about the cause or consequences of the traumatic event, leading to blame of self or others.

Persistent negative emotional state (e.g., fear, horror, anger, guilt, shame).

Markedly diminished interest or participation in significant activities.

Feelings of detachment or estrangement from others.

Persistent inability to experience positive emotions.

Alterations in Arousal and Reactivity


Irritable behavior and angry outbursts (with little or no provocation).

Reckless or self-destructive behavior.

Hypervigilance.

Exaggerated startle response.

Problems with concentration.

Sleep disturbances (difficulty falling or staying asleep, restless sleep).

Duration and Impact 


Duration: Symptoms must last for more than one month to be considered PTSD.

Impact: The symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning.

Obsessive-Compulsive Disorder (OCD) is a chronic mental health condition characterized by persistent, intrusive thoughts (obsessions) and repetitive behaviors or mental acts (compulsions) that an individual feels driven to perform. These obsessions and compulsions can cause significant distress and interfere with daily functioning.

Key Features

Obsessions: Recurrent and persistent thoughts, urges, or images that are intrusive and unwanted, causing marked anxiety or distress.

Common Themes

Contamination (e.g., fear of germs), harm (e.g., fear of causing harm to oneself or others)

Symmetry (e.g., needing things to be in order or symmetrical), forbidden or taboo thoughts (e.g., aggressive, sexual, or religious thoughts)

Compulsions: Repetitive behaviors (e.g., handwashing, checking) or mental acts (e.g., counting, repeating words silently) that an individual feels driven to perform in response to an obsession or according to rules that must be applied rigidly.

Compulsions are aimed at preventing or reducing anxiety or distress, or preventing some dreaded event or situation; however, these behaviors or mental acts are not connected in a realistic way to what they are designed to neutralize or prevent, or they are clearly excessive.

Diagnostic Criteria (DSM-5-TR)

Presence of Obsessions, Compulsions, or Both: The individual experiences obsessions, compulsions, or both.

Time-Consuming: The obsessions or compulsions are time-consuming (e.g., taking more than one hour per day) or cause clinically significant distress or impairment in social, occupational, or other important areas of functioning.

Not Attributable to Substance Use or Medical Condition: The symptoms are not due to the physiological effects of a substance or another medical condition.

Not Better Explained by Another Mental Disorder: The symptoms are not better explained by the symptoms of another mental disorder (e.g., generalized anxiety disorder, body dysmorphic disorder).

Bipolar disorders are a group of mental health conditions characterized by significant mood swings that include emotional highs (mania or hypomania) and lows (depression). These mood changes can affect energy levels, activity, judgment, behavior, and the ability to carry out daily tasks.

Types of Bipolar Disorders

Bipolar I Disorder. Characterized by at least one manic episode that may be preceded or followed by hypomanic or major depressive episodes.

Manic Episode: A period of abnormally elevated, expansive, or irritable mood and increased activity or energy lasting at least one week, severe enough to cause significant impairment or necessitate hospitalization.

Symptoms of Mania:

• Inflated self-esteem or grandiosity
• Decreased need for sleep
• More talkative than usual or pressure to keep talking
• Flight of ideas or subjective experience that thoughts are racing
• Distractibility
• Increase in goal-directed activity or psychomotor agitation
• Excessive involvement in activities with high potential for painful consequences (e.g., unrestrained spending sprees, sexual indiscretions) 

Bipolar II Disorder.
Characterized by at least one hypomanic episode and one major depressive episode, without ever having a full manic episode.

Hypomanic Episode: Similar to a manic episode but less severe and lasting at least four days. It is not severe enough to cause significant impairment or require hospitalization.

Major Depressive Episode: A period of at least two weeks with five or more symptoms of depression, such as persistent sadness, loss of interest or pleasure, changes in weight or appetite, insomnia or hypersomnia, fatigue, feelings of worthlessness or excessive guilt, difficulty concentrating, and recurrent thoughts of death or suicide. 

Cyclothymic Disorder. Characterized by numerous periods of hypomanic symptoms and depressive symptoms lasting for at least two years (one year in children and adolescents) that do not meet the full criteria for a hypomanic episode or major depressive episode.

Symptoms: Mood swings involving hypomania and depressive symptoms, but the symptoms are less severe than those required for a diagnosis of Bipolar I or II disorder.

Common Symptoms Across Bipolar Disorders

Manic/Hypomanic Symptoms o Elevated or irritable mood o Increased energy and activity

Decreased need for sleep o Racing thoughts

Rapid speech o Impulsivity and risky behaviors

Grandiosity

Depressive Symptoms

Persistent sadness or low mood

Loss of interest or pleasure in activities

Changes in appetite or weight o Sleep disturbances (insomnia or excessive sleeping) o Fatigue or loss of energy

Feelings of worthlessness or excessive guilt

Difficulty concentrating

Thoughts of death or suicide 

Somatic Symptom Disorder (SSD) is a mental health condition characterized by an excessive focus on physical symptoms—such as pain or fatigue—that cause significant distress and impairment in daily functioning. The symptoms are real and may or may not be associated with a diagnosed medical condition, but the individual's reaction to them is disproportionate and persistent.

Key Features

Presence of Physical Symptoms. One or more physical symptoms that are distressing or result in significant disruption of daily life. These symptoms can include pain, gastrointestinal issues, fatigue, or other bodily complaints.

Excessive Thoughts, Feelings, or Behaviors
• Disproportionate and persistent thoughts about the seriousness of one's symptoms.
• Persistently high levels of anxiety about health or symptoms.
• Excessive time and energy devoted to these symptoms or health concerns. 

Duration. The state of being symptomatic is persistent, typically lasting more than six months, although the specific symptoms may change over time.

Diagnostic Criteria (DSM-5-TR).To be diagnosed with Somatic Symptom Disorder, an individual must meet the following criteria:
• One or more somatic symptoms that are distressing or result in significant disruption of daily life.
• Excessive thoughts, feelings, or behaviors related to the somatic symptoms or associated health concerns as manifested by at least one of the following:
o Disproportionate and persistent thoughts about the seriousness of the symptoms.
o Persistently high level of anxiety about health or symptoms.
o Excessive time and energy devoted to these symptoms or health concerns.
• Although any one somatic symptom may not be continuously present, the state of being symptomatic is persistent (typically more than six months).

Impact on Daily Life
• Impairment: The excessive concern with physical symptoms can lead to significant impairment in social, occupational, and other important areas of functioning.
• Healthcare Utilization: Individuals with SSD often visit multiple healthcare providers and undergo numerous medical tests and procedures, which can lead to increased healthcare costs and potential medical risks. 

Dissociative disorders are mental health conditions characterized by disruptions or discontinuities in consciousness, memory, identity, emotion, perception, body representation, motor control, and behavior. These disruptions can affect a person's sense of self and reality, often resulting from trauma or extreme stress.

Key Types of Dissociative Disorders

Dissociative Identity Disorder (DID). Previously known as multiple personality disorder, DID is characterized by the presence of two or more distinct personality states or identities, each with its own pattern of perceiving, relating to, and thinking about the environment and self.

Symptoms
• Discontinuity in sense of self and sense of agency.
• Recurrent gaps in memory for everyday events, important personal information, and traumatic events.
• Each identity may have its own name, age, history, and characteristics.

Dissociative Amnesia. Characterized by an inability to recall important autobiographical information, usually of a traumatic or stressful nature, that is inconsistent with ordinary forgetting.

Types
• Localized Amnesia: Loss of memory for a specific period.
• Selective Amnesia: Loss of memory for some but not all events during a specific period.
• Generalized Amnesia: Complete loss of memory for one's life history. o Symptoms: Sudden inability to remember personal information, leading to significant distress or impairment.

Depersonalization/Derealization Disorder. Characterized by persistent or recurrent experiences of depersonalization (feeling detached from one's own mind, self, or body) and/or derealization (experiences of unreality or detachment from one's surroundings).

Symptoms
Depersonalization: Feeling like an outside observer of one's thoughts, feelings, body, or actions. 
Derealization: Feeling as if the external world is unreal or distorted.

Insight: Individuals with this disorder typically maintain reality testing, meaning they are aware that their experiences are not normal and are not truly detached from reality.

Causes
Trauma: Dissociative disorders are often associated with traumatic experiences, especially during childhood, such as abuse, accidents, or natural disasters.
• Stress: Extreme stress can trigger dissociative symptoms, even without a history of trauma.
• Psychological Factors: Factors like coping mechanisms and defense strategies developed in response to trauma can contribute to the development of dissociative disorders.

Schizophrenia is a chronic and severe mental health disorder characterized by disturbances in thought, perception, emotion, and behavior. It often involves psychotic experiences, such as hallucinations and delusions, which can significantly impair an individual's ability to function.

Key Features

Positive Symptoms
• Hallucinations: Sensory experiences that appear real but are created by the mind. The most common are auditory hallucinations, such as hearing voices.
• Delusions: Strongly held false beliefs that are not grounded in reality. Examples include delusions of persecution, grandiosity, or control.
• Disorganized Thinking: Incoherent speech and thought patterns, making it difficult to communicate effectively. 
• Disorganized or Abnormal Motor Behavior: This can range from childlike silliness to unpredictable agitation.

Negative Symptoms
• Affective Flattening: Reduced expression of emotions, such as facial expressions or voice tone. 
• Alogia: Poverty of speech or reduced verbal output.
• Anhedonia: Inability to experience pleasure from activities usually found enjoyable.
Avolition: Lack of motivation to initiate and sustain purposeful activities.

Cognitive Symptoms
Impaired Executive Functioning: Difficulty with planning, decision-making, and problem-solving.
• Attention Deficits: Trouble focusing or paying attention.
• Memory Impairments: Problems with working memory, which affects the ability to use information immediately after learning it. Diagnosis (DSM-5-TR Criteria).

To be diagnosed with schizophrenia, an individual must experience at least two of the following symptoms for a significant portion of time during a one-month period, and at least one of these must be delusions, hallucinations, or disorganized speech:
• Delusions
• Hallucinations
• Disorganized speech
• Grossly disorganized or catatonic behavior
• Negative symptoms Additionally, symptoms must persist for at least six months and significantly impair functioning in one or more major areas of life, such as work, interpersonal relations, or self-care.

Causes
• Genetic Factors: A higher risk is associated with having a family history of schizophrenia. • Brain Chemistry and Structure: Imbalances in neurotransmitters (e.g., dopamine and glutamate) and structural abnormalities in the brain.
• Environmental Factors: Prenatal exposure to viruses, malnutrition, stress, and psycho-social factors.